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病毒 肝炎

Overview

几种不同的病毒可以感染肝脏,引起被称为肝炎的炎症. The most prevalent of these in the United States are hepatitis A, B and C.

甲型肝炎

甲型肝炎 is acquired from contaminated food or water. 在健康个体中, it causes an acute illness with fever, loss of appetite and jaundice lasting two to three weeks. Complete recovery is the rule, followed by life-long immunity to the virus. In people with pre-existing advanced liver disease, acute hepatitis A tends to be severe and can be fatal.

乙型肝炎

Acquired through exposure to the blood or secretions of an infected person, hepatitis B also can be transmitted through sexual contact. 新生儿可能在出生时从患有活动性乙型肝炎的母亲那里获得这种病毒.

感染乙型肝炎的成年人患有急性疾病,从非常轻微的疾病开始, 只有流感样症状, ,恶心, 腹痛和黄疸.

Most people with the condition recover and develop immunity, but 5 percent to 10 percent become persistently infected, and have the potential to infect others. For infants who are exposed at birth and do not receive treatment, the rate of chronic infection is much higher. 长期患有活动性乙型肝炎的人,年龄超过20年,有发展成乙型肝炎的风险 肝癌.

丙型肝炎

目前,丙型肝炎的主要传播方式是通过使用感染者的针头注射非法药物. 在对血库进行检测之前,这种疾病是通过输血传播的. Unlike hepatitis B, the rate of sexual transmission is low.

The acute illness is frequently very mild. 然而,许多人未能清除病毒,因此约70%的人成为慢性感染者. 估计有400万美国人患有丙型肝炎,其中许多人并不知道自己的病情.

The virus causes inflammation that slowly and insidiously, 在20到30年间, 导致肝脏的疤痕. 随着病情的发展,第一个症状可能只是精力下降. As the liver disease becomes significant, patients may experience retention of fluid, causing swelling of the ankles and increased weight, 内出血和神志不清. 疾病进展的速度是可变的,原因只是部分了解. It is clear that heavy alcohol use accelerates the pace of disease. In people who develop advanced scarring of the liver, a condition known as 肝硬化,发展的风险 肝癌 是重要的.

我们治疗病毒性肝炎的方法

加州大学旧金山分校为所有形式的病毒性肝炎患者提供最先进的诊断和治疗选择. Our approach depends on the type and severity of the disease. 甲型肝炎 usually resolves on its own, so we help patients manage their 症状 and avoid spreading the infection. 我们用最新的药物疗法治疗慢性乙型肝炎或丙型肝炎.

如果患者对治疗没有反应,或者直到出现肝病症状才知道自己感染了这种病毒,慢性肝炎感染可能导致严重的肝损伤或肝功能衰竭. In these cases, a liver transplant may be necessary. Our liver transplant program, designated a center of excellence by the U.S. Department of Health and Human Services, 以卓越的成果和帮助开创移植技术而闻名,这些技术使移植更安全、更成功. We perform more than 200 transplants each year, and our survival statistics are among the very best in the country.

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  • One of the nation's best in gastroenterology & 胃肠道手术

迹象 & 症状

随着病毒性肝炎发展到晚期,可能会引起以下一种或多种症状:

  • 食欲不振
  • 恶心和/或呕吐
  • 发热
  • 尿色深
  • 胃疼
  • 乏力
  • Yellowing of the skin and eyes, called jaundice
  • 情绪变化,健忘
  • Black bowel movements, which indicate bleeding into the intestine

诊断

在诊断肝炎时, blood tests are performed to detect the hepatitis virus, 还有病毒的抗体. The tests also distinguish between an acute or chronic infection.

治疗

根据疾病的类型和严重程度,肝炎的治疗方法各不相同.

甲型肝炎治疗

There is no specific therapy for acute hepatitis A infection. 因此,预防是关键. 一种有效的疫苗是可用的,建议所有肝病患者接种. 还建议计划前往十大赌博平台排行榜上卫生十大赌博靠谱网络平台可能不太理想的地区的人接种疫苗.

在接种疫苗之前, 患者通常会接受血液检查,以检查是否已经存在对病毒的抗体, in which case vaccination is unnecessary.

乙型肝炎治疗

大约25%的慢性乙型肝炎患者可以通过一种名为聚乙二醇化干扰素- α的药物治愈, which is taken as a weekly injection for six months. 另一种选择是用口服药物抑制病毒,如拉米夫定和阿德福韦. 对于病毒水平升高和肝脏疾病进展的患者,推荐使用抑制疗法.

In people with a possible exposure to hepatitis B, such as health care workers and sexual partners of infected persons, an effective vaccine exists and is recommended. 除了, 通过给婴儿接种乙肝疫苗和注射乙肝免疫球蛋白,可以在很大程度上预防乙肝母婴传播.

丙型肝炎治疗

目前, 丙型肝炎最有效的治疗方法是由聚乙二醇化干扰素和利巴韦林组成的药物组合. 聚乙二醇化干扰素每周注射一次,利巴韦林每天服用两次. 这种治疗是化疗的一种形式,每个人对它的耐受能力差异很大.

患者的反应将取决于特定类型的丙型肝炎,即“基因型”.在美国.S., genotypes 1, 2 and 3 account for most cases. 干扰素-利巴韦林治疗了大约40%的基因1型病例和80%的基因2型或3型病例. 其他提高病人治愈机会的因素包括低病毒水平, normal liver function and normal weight.

对大多数人来说, interferon-ribavirin causes flu-like 症状 with muscular aches, 易怒, 食欲不振,情绪低落. 还可能出现皮疹和脱发. Interferon and ribavirin both reduce blood cell counts, which may require dose reduction or discontinuation of treatment. Regular laboratory testing during the treatment is essential.

Some people find they cannot continue to work on this regimen, 基因型1持续48周基因型2和3持续24周. 最后,药物的成本很高,使得保险必不可少.

肝移植

肝脏移植手术 可能是肝炎进展为肝功能衰竭,治疗无效或不能耐受治疗的人的一种选择吗. 目前, almost one half of all liver transplants in the U.S. are performed for end-stage hepatitis C.

移植的评估很复杂,通常需要几个月的时间. 因此, 即使患者感觉良好,也应该在出现肝功能衰竭的第一个迹象时进行移植, 或者通过x光检查或肝活检诊断出患有晚期肝病.

加州大学旧金山分校健康 medical specialists have reviewed this information. 它仅用于教育目的,并不打算取代您的十大赌博平台排行榜或其他医疗保健提供者的建议. 我们鼓励您与您的供应商讨论您可能遇到的任何问题或疑虑.

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